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Overexpression of Twist1 and Twist2 in BM-MSCs increased STRO-1 expression (a stemness marker), promoted proliferation and adipogenesis, but inhibited osteogenesis and chondrogenesis, suggesting they help maintain MSC stemness [1]

A company selling IGF-1 LR3 with testimonials about muscle growth, recovery benefits, or anti-aging effects is distributing an unapproved new drug, even if the label says "not for human consumption." The agency does not require proof of actual human useintent inferred from marketing is sufficient for enforcement

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As is the case for SCOPAs hepatoprotective properties, investigations have focused on SCOPA-containing TCM preparations or on single compounds isolated from SCOPA, but Cho et al