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15 Varenicline is highly effective but currently unavailable in New Zealand Varenicline is a nicotinic receptor partial antagonist, funded with Special Authority approval as a second line option for patients who have tried unsuccessfully to quit smoking after: At least two separate trials of NRT, with at least one of these attempts involving comprehensive advice on NRT use

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Majority of cardio-vascular and lung disorders Burden of tobacco use Almost 40% of TB deaths are associated with smoking

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