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But there are times when bloating happens in response to a more serious underlying cause, such as: Cancer, including ovarian, uterine, colon, pancreatic or stomach cancer Digestive diseases, such as IBS, pelvic inflammatory disease (PID), small intestinal bacterial overgrowth (SIBO) or GERD Mental health issues such as anxiety or depression Medical procedures or surgeries that involve pumping gas into the stomach Medication containing acarbose, lactulose or sorbitol Call your PCP if your bloating doesnt improve in a few days or if you have any of the following symptoms: Bloody stool Diarrhea Fever following surgery Nausea or vomiting Vaginal bleeding Unexplained weight loss Worsening heartburn

Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or References Burton S L, Gitchell J G, Shiffman S

Inflammation also plays a role in Alzheimers disease, heart disease and cancer