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Cannabis was not commonly smoked directly until tobacco came into widespread use in the 16th century

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Another report by the same researchers, published in February of 2012 in the journal Nicotine & Tobacco Research indicates that this could be true: Experienced e-cigarette smokers had higher nicotine levels and heart rates after they started inhaling nicotine, so they were basically better at smoking the e-cigarette and reliably got the nicotine high they were looking for, about equivalent to smoking tobacco cigarettes

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