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There was little to no dose-dependent effect of PEA on global rsFC

10.1007/BF02975691 17 AtkinsR

A lookback period of no less than 12 months and no longer than 15 months prior to posting the MRF, as described in more detail earlier in this section, provides for a more consistent lookback period across hospitals than a static 12-month lookback period, which we believe helps to alleviate commenters' concerns about having varying amounts of data from which to encode the allowed amounts for an item or service and the complexity of a segmented lookback period if a contract changes midyear

Additionally, AS-IV can competitively inhibit CYP1A2 activity, subsequently decreasing the clearance rate of theophylline (Zhang et al., 2013)