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Troubleshooting: If headloss is increasing more rapidly than expected, it could indicate that the media is fouled or that biofilm overgrowth is causing excessive flow resistance

(PubMed) Anand P, Kunnumakkara AB, Newman RA, Aggarwal BB

It is also not known whether vitamin B 12 can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity

92,93 However, in the latter patient population, B12 has shown some benefits when used alongside other approaches including light therapy and drugs, although these studies had some methodological weaknesses, making it difficult to interpret the results