Phthalimidinoglutarimide-C3-O-PEG3-C2-Br deuterium-labeled-alcohol 6 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CO)C(C)(C)C)C=C1 Purity (HPLC)

6 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CO)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

11 (TFA Salt) SMILES: NCCNC(=O)C1=CC=C2C(=C1)C(=O)OC21C2=CC=C(O)C=C2OC2=C1C=CC(O)=C2

NCCC#CC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

85 SMILES: Cl

Phthalimidinoglutarimide-C3-O-PEG3-C2-Br deuterium-labeled-alcohol 6 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CO)C(C)(C)C)C=C1 Purity (HPLC)Degrader building block for targeted protein degradation. Contains an E3 ligase ligand with a linker and a function group, which can be conjugated to target protein ligands through straightforward chemical reactions. Product Name Phthalimidinoglutarimide C3 O PEG3 C2 Br Synonyms Phthalimidinoglutarimide 4' C3 O PEG3 C2 Br CAS Number n a Related CAS Molecular Formula C24H33BrN2O7 Molecular Weight 541. 439 SMILES