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In contrast, derivatives of zidovudine (127, 128), glutathione conjugate of L-dopa (126), modified glutathione derivative of L-dopa (151), dopamine-gluconamine and gluconamide (140) as well as ketoprofen derivatives (113) demonstrated pharmacological activity and should be considered as analogues

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Components required for detoxifying reactive oxygen species include AhpC-associated systems, which depend on thiol reduction for regeneration, SodM (superoxide dismutase), and thioredoxin (TrxA), ensuring protection against oxidative damage and maintenance of protein integrity

Moreover, although personalized medicine provides one-on-one treatment for patients, which further improves the treatment plan for patients and is conducive to their further recovery and improvement in their quality of life, the associated cost may be high for ordinary people