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Environmental and lifestyle factors such as UV radiation, pollution, psychological stress, alcohol consumption, smoking, inflammation, and chronic diseases exacerbate oxidative stress, complicating efforts to prevent or treat premature graying.5 Understanding the underlying mechanisms of hair graying is crucial for developing strategies to prevent or reverse age-related changes in regenerative tissues

showed the changes of NMR chemical shift caused by the chelation of peptide to calcium ions, which affects the electron density around the peptide protons

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Rec Nat Prod 12(4):397402 Harborne JB, Baxter H, Moss GP (1999) Phytochemical dictionary: Handbook of bioactive compounds from plants, 2nd edn