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doi: 10.1038/nrm3565 79

Symptoms may include: In cases of high creatinine due to medication toxicity: If a kidney infection (pyelonephritis) develops and treatment is neglected, the following symptoms may occur: In cases of glomerulonephritis, the symptoms associated with high creatinine may include: In cases of kidney failure, symptoms may include: Similar symptoms may also arise in conditions that can lead to kidney function impairment, such as high blood pressure, urinary tract obstruction, and heart disease

Based on these effects, chitosan can be considered for the improvement of various hemorrhagic hemorrhoids (A summary of polysaccharides with hemorrhoid improvement potential is provided in Table 4)