Azide-Hexanoyl-Val-Cit-PAB(m-PEG8)-MMAE Size:1mg SulfoCy3-CA CAS Number Related CAS

SulfoCy3-CA CAS Number Related CAS Molecular Formula C40H56ClN3O9S2 Molecular Weight 822

this construct supports efficient antibody conjugation

1038/nature18621

51 SMILES OCCOCCOCCOCCOCC#CC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Azide-Hexanoyl-Val-Cit-PAB(m-PEG8)-MMAE Size:1mg SulfoCy3-CA CAS Number Related CASSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing