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In 2019, an estimated 40 percent of all new cancer cases diagnosed in the United States (US) were attributable to modifiable risk factors including: cigarette smoking, ultraviolet (UV) radiation, excess body weight, alcohol consumption, physical inactivity, and infectious agents (163)Islami F, et al

Jan 3, 2026 Dark circles under eyes create persistent cosmetic concern affecting appearance across all ages and skin types, with multiple underlying causes including thin periorbital skin revealing underlying vasculature, hyperpigmentation from melanin accumulation, shadows from volume loss and fat pad descent, and fluid retention creating puffiness accentuating darkness