NRX-252114 amine-amine 854 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCCN=[N+]=[N-])CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC)

854 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCCN=[N+]=[N-])CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Pomalidomide-CO-C4-Br Synonyms Pomalidomide-4'-CO-C4-Br CAS Number 2162120-76-3 Related CAS Molecular Formula C18H18BrN3O5 Molecular Weight 436

Product Name 4-bromo-3-(methoxy-d3)-benzaldehyde Synonyms CAS Number n/a Related CAS Molecular Formula C8H7BrO2 Molecular Weight 218

1038/s41557-019-0371-1

NRX-252114 amine-amine 854 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCCN=[N+]=[N-])CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC)NRX 252114 is an enhancer of the interaction between beta catenin and beta TrCP. NRX 252114 acts as molecular glue in cells to promote the ubiquitylation and subsequent degradation of mutantbeta catenin by the 26S proteasome. Product Name NRX 252114 Synonyms CAS Number 2763260 39 3 Related CAS Molecular Formula C22H12Cl2F3N3O2S Molecular Weight 510. 31 SMILES FC(F)(F)C1=CC(SC2=C(Cl)C=CC=C2Cl)=C(C(=O)N2CC3=CC=CC(C#N)=C3C2)C(=O)N1 Purity (HPLC) >= 95%