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10.1016/j.jaad.2020.06.881 51 HazneciE.KarabulutA

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CD8+ T cells have a crucial role in tumor immunity resulting in part from the release of different cytotoxic molecules (for example, granzyme B, perforin)

Martin VT, Goldstein JA

AKT is a key regulator in the insulin signaling pathway and regulates several downstream proteins, such as the transcription factor FOXO1, glycogen synthase kinase 3 (GSK3) as well as mTOR and Forkhead transcription factors [65, 66]