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It has been extensively studied in preclinical and laboratory research for its role in cellular communication, tissue remodeling, and regenerative biochemistry

The findings reveal that Lactobacillus iners , an L-lactate-producing bacterium in tumors, is linked to decreased patient survival and induces resistance to chemotherapy and radiation by altering tumor metabolic pathways ( Figure 1 Table 1 The role and mechanisms of gut microbiota-derived metabolites in anti-tumor immunity, cancer immunotherapy and chemotherapy

while 10 M of tamoxifen did not stimulate P-gp ATPase (supplemental Fig