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In humans, P25 has been linked to several diseases, including not only Alzheimers but also Parkinsons disease and frontotemporal dementia

Chen H, Qin S, Lei A, Li X, Gao Q, Dong J, et al

In addition to a decrease of the otherwise raised blood pressure values, NaBPC157 also caused a marked attenuation or even abolition of the lesions and disturbances normally appearing in the various organs which were (after three weeks of an increased salt diet in the controls): very severe hyaline degeneration with prominent parenhymaous hemorrhages, degeneration of the arterial walls, vacuolisation of the cells in the heart, severe congestion (specifically medullar) in the adrenals, severe congestion, parenhymatous hemorrhage with hematuria in kidney and hemosiderosis and erythrocytophagia in the spleen