Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8) peg6 OC1=CC2=C(C=C1)C1(OC(=O)C3=CC=C(C=C13)C(=O)NCCCN=[N]#N)C1=CC=C(O)C=C1O2 Purity (HPLC): ≥ 95%
Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8) peg6 OC1=CC2=C(C=C1)C1(OC(=O)C3=CC=C(C=C13)C(=O)NCCCN=[N]#N)C1=CC=C(O)C=C1O2 Purity (HPLC): ≥ 95%SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. Derived from established
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