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Fractionated radiation induces an increase in IGF1 secretion level and gradually up-regulates IGF1R expression in cancer stem cells (GSCs) (Osuka et al., 2013

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doi: 10.3324/haematol.2014.113852 152 Cartledge WolfDMLanghansSA

It is also critical for blood sugar stability, bile production, breakdown of fats, production of cholesterol, formation of ketones, assisting the regulation of proper hormone levels, and other health functions