Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE protac ligand exhibited longer fluorescence lifetimes than

exhibited longer fluorescence lifetimes than its non-sulfonated counterparts

78 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCCC(O)=O)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name BG-Nor Synonyms NorBG CAS Number Related CAS Molecular Formula C22H24N6O3 Molecular Weight 420

enabling further purification and detection

Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE protac ligand exhibited longer fluorescence lifetimes thanSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to