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Description

Ischemia-induced glutamate excitotoxicity depletes cystine availability, compromising glutathione synthesis and inactivating GPX4, thereby removing the critical brake on lipid peroxidation

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S., Hunstad, D

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279 PI3K/AKT signaling PI3K in the lipid kinase family interacts with the PH domain of the AKT protein (also known as PKB), inducing its conformational change and AKT phosphorylation

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