foxo4 dri peptide senolytic 2024 study FOXO4-DRI improves spermatogenesis in aged mice through reducing senescence-associated secretory phenotype secretion Peptide inhibitors targeting FOXO4-p53 interactions

Peptide inhibitors targeting FOXO4 p53 interactions and inducing senescent cancer cell specific apoptosis bioRxiv Frontiers FOXO4 DRI regulates endothelial cell senescence via the P53 signaling pathway FOXO4 DRI improves spermatogenesis in aged mice through reducing senescence associated secretory phenotype secretion from Leydig cells ScienceDirect The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications

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