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According to Abhinav Agrawal, MD, director of interventional pulmonology and bronchoscopy at Northwell Health, One of the issues with legalization is that it contributes to the false perception that risk is low, he says

E-cigarettes are battery-operated devices that produce an aerosol by heating substances typically containing nicotine and/or other materials or flavorings on an internal metal coil until the material is aerosolized and can be inhaled [2, 3]

Autoxidation of fragrance terpenes contributes greatly to fragrance allergy, which emphasizes the need of testing with compounds that patients are actually exposed to and not only with the ingredients originally applied in commercial formulations. Styrene Turpentine 2