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The nicotine in these medicines is delivered through a controlled dose that is reduced over time

As shown in Supplementary Table S1 online, the full range of available LD50 values in different animal species is taken into account as a risk function assuming a normal distribution for BMDL10 rather than that a single value is entered into the calculation (except methamphetamine and MDMA for which only one value was available in the literature)

He hasnt gotten it through yet, but it remains on the agenda

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