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Pharmacological and genetic targeting of mitochondrial dynamics pathways has been investigated in a number of different disease models (Whitley et al., 2019), yet attempts in PD are limited

Anthracyclines induce double-strand DNA breaks at active gene promoters

The anti-inflammatory effect of bilirubin can be side-stepped by the fact that serum bilirubin is negatively related to the markers of oxidative stress in serum (146, 147) and markers of inflammation such as C-reactive protein levels (148, 149)

in one study 74 out of 78 stable elements could be detected in salmon (Haraguchi et al., 2008), and 60 or more elements have been reported in human tissues (Chellan & Sadler, 2015)