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time for an overdue clinical study

Al-Ayadhi L, Alhowikan AM, Bhat RS, El-Ansary A

Notably, XKR8 KO BMNs failed to generate both filamentous chromatin structures and the citrullinated histones, suggesting a disruption in upstream NET signaling, particularly in Ca 2+ signaling pathways, given that peptidylarginine deiminase 4 (PAD4) activation is calcium-dependent 34