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Normalization method that resulted with a normal distribution of the data was chosen and varied between datasets (Supplementary Data 1)

GSH depletion causes oxidative stress and lipid peroxidation To evaluate the downstream effects of GSH depletion, we measured soluble ROS in RPE cells treated with Cys 2 starvation, BSO, or erastin by flow cytometry using the fluorescent probe H 2 DCFDA

Ginsenosides from Panax ginseng and Panax notoginseng have been found to promote vasodilation by increasing NO bioavailability and endothelial responsiveness

doi: 10.1371/journal.pone.0151465 125 SorianoCMukaroVHodgeGAhernJHolmesMJersmannHet al