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(PubMed) Reid ME, Duffield-Lillico AJ, Slate E, et al

Using less water will result in a more concentrated solution (more mcg per unit), while more water will make it more dilute.

There was no significant effect on plasma concentrations 1hrPrEX

Similarly, in traditional Western herbal medicine, licorice is classified as an adaptogenic plant, and used as an adrenal tonic to help improve resilience against the negative physical, mental and emotional impacts of acute or chronic stress