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83 In vitro, knockdown of TYK2 in murine and human MPNST cells significantly increased cell death, while knockdown in vivo led to a decreased tumour volume in a subcutaneous mouse model, supporting a role for TYK2 in driving MPNSTs

10.1002/hep.21763 Hepatology 146 QuinlanC

For example, sulfoxidation of S -allyl-L-cysteine and S -benzyl-L-cysteine and, at a lower rate, S -(1,2-dichlorovinyl)-L-cysteine and S -(1,2,2-trichlorovinyl)-L-cysteine, was catalyzed by flavin monooxygenases (Ripp et al

Crit Care Med 20:8093 [DOI] [PubMed] [Google Scholar] Muirhead H, Clayden DA, Barford D, Lorimer CG, Fothergill-Gilmore LA, Schiltz E, Schmitt W (1986) The structure of cat muscle pyruvate kinase