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Lokman P, Jennifer H, Mariah G A, Xia L, Matthias E, Ashwini L C

The earliest signs of alcoholic liver damage tend to be subtle or nonspecific such as: As liver injury progresses, more evident signs arise: Even advanced liver disease can develop without overt symptoms until sudden complications like variceal bleeding or hepatic encephalopathy arise

Studies have shown that cancer patients with high expression of FASN have a poor prognosis and shorter overall survival, and high FASN expression is strongly associated with a poor chemotherapy response and immunosuppression [219, 220]

The growth-restricted fetus/newborn is characterized by an increased fetal and neonatal mortality and morbidity[177, 178] and an increased risk of clinical disorders in adult life, such as cardiovascular disease, diabetes and obesity[179, 180]