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Landmark Phase II Clinical Trial Demonstrating Significant Weight Reduction With Cagrilintide Through Long-Acting Amylin Receptor Agonism In Adults With Overweight And Obesity

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While GLP-1 and GIP receptor activation primarily reduce energy intake through appetite suppression and delayed gastric emptying, glucagon receptor activation continues to drive energy expenditure through thermogenesis and hepatic fat oxidation regardless of whether caloric intake has already decreased