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Research has shown that neuromelanin can trigger inflammation through the NF-kappa B-dependent and p38 mitogen-activated protein kinase-dependent pathways in primary microglia derived from rats [56]

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Nutrients 13, 2536

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DA progenitor induction and transplant DA progenitors were induced as previously described 13

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Furthermore, the potential toxicity of NPs in the treatment of PD is a significant concern, especially when considering long-term use or large doses

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