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Nutrient solution was maintained full in the container, and a ventilation pump ensured the solution had enough oxygen

[Google Scholar] 52.Dhandapani KM, Mahesh VB, and Brann DW

Studies in apoE-deficient mice expressing amyloid protein precursor (APP)-V717F demonstrated that apoE is actually required for amyloid plaque formation, at least in mice (Bales et al., 1999)