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Ann Rheum Dis (1968) 27(1):4954

This suggests: Ongoing cellular damage from free radicals Increased inflammation throughout the body Accelerated aging at the cellular level Higher risk of chronic diseases The danger: Youre fighting a losing battle against oxidative damage, which can lead to cardiovascular disease, neurological decline, cancer, and autoimmune conditions

CA1-specific HDAC9 deletion impairs cognitive function in young mice To determine the role of HDAC9 specifically within the hippocampal CA1 region, we employed the Cre/loxP system to induce region-specific deletion of HDAC9 in adult mice (46 months old)

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