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Moreover, the activation of Sat1 has been shown to promote lipid peroxidation, rendering cells more susceptible to oxidative stress and contributing to the development of ferroptosis ( In this study, the induction of ferroptosis in MIRI was observed

It has negligible systemic toxicity and has been administered in humans at high dosages (up to 12 g/day for 3 months) without significant adverse effects (Ma et al., 2019)