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486 Nrf2 can activate the transcription of a series of antioxidant genes and block ferroptosis, playing a protective role in DOX-induced cardiomyopathy by regulating oxidative stress and autophagy

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Furthermore, TrxR inhibition by different gold-based compounds induces ferroptosis in KRAS-WT lung cancer [103] , triple-negative breast cancer cells [104] , and hepatic cells [105]