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A randomized controlled trial published in PMC demonstrates that older humans (71.1 years) exhibited significantly lower glutathione levels, impaired mitochondrial fatty-acid oxidation, reduced gait speed and physical function, and higher oxidative stress compared to young controls (25.5 years)

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Previously, single-cell RNA sequencing of mouse ovarian oocytes during the transition from the pre-follicular stage to the follicular stage indicated that follicular atresia may be associated with the ferroptosis pathway (Wang JJ

Antioxid Redox Signal (2015) 22:67985