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4,5 Without adequate disease control, UC may result in gastrointestinal symptoms such as bloody diarrhoea, faecal urgency, incontinence, abdominal pain, fatigue, weight loss and nutritional deficiencies, together with extraintestinal manifestations that include arthritis, skin disease and iritis

Thus, the NADPH-dependent reduction of oxidized glutathione to maintain a steady state of glutathione is needed for GSH activity [1]

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