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Alcohol and its breakdown products affect liver genes and DNA

10.1093/brain/awm304 Brain 7 BosM

The cDNA for SLC7A11 coding region was amplified from ZR-75-1 breast cancer cell line using standard RT-PCR and ligated into EcoR I- Sal I linearized retroviral pBabe-hygro vector, generating the pBabe-hygro-SLC7A11

Understanding these epigenetic mechanisms can help identify how variations in ACL geometry might predispose individuals to injuries and guide the development of personalized prevention and treatment strategies