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While thresholds exist to characterize ruminal acidosis, the specific pH value at which damage occurs to the ruminal epithelium, microbial community structure and activity are altered, and feed intake is depressed likely varies among individual animals

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Cell death signaling pathways in ischemic stroke Damage caused by excitotoxicity, oxidative stress, and mitochondrial dysfunctions in ischemic stroke may induce a variety of cellular signaling cascades, which lead neural cells to undergo either programmed or unprogrammed death

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