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Gastroenterology 108:761 Ruenzi M, Stolte M, Veljaca M, Oreskovic K, Peterson J, Ulcerative Colitis Study Group (2005) A multicenter, randomized, double blind, placebo-controlled phase II study of PL 14736 enema in the treatment of mild-to-moderate ulcerative colitis

Interestingly, in contrast to growth hormone insensitivity (GHI), the IGF-I deficient animals are neurologically impaired, as was also reported in a single patient with a defect in the IGF-I gene[40]

Supporting Heart Health and Preventing Anemia A deficiency in vitamin B12 can lead to pernicious anemia, a condition where the body can't produce enough healthy red blood cells