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Mitochondrial and glucose metabolic dysfunctions in granulosa cells induce impaired oocytes of polycystic ovary syndrome through sirtuin 3

Paralleling the evidence, the dysregulated lipid metabolism and the lowered availability of lipid-soluble vitamins with exposure to mycotoxins direct the pressure on osteocytes to release the calcium into the circulation, thus moving toward osteoporosis in a long-term perspective ( Oxidative Stress, Mycotoxin Path to Cell's and System's Dysfunction Obstruction of the arteries (supplying blood to different tissues), defined as arterial dysfunction, is mainly the buildup of oxidative reactions and calcium and inflammatory deposits restoring each other ( A significant consequence of the enhanced ROS formation and prolonged oxidative stress exposure is endothelial dysfunction via scavenging of NO by superoxide