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(2017) 313:R64653

Mudd PA, Crawford JC, Turner JS, Souquette A, Reynolds D, Bender D, et al

THF can be directly converted to 5,10-methylene-THF by the vitamin B 6 -dependent enzyme serine hydroxymethyltransferase (SHMT), resulting in the formation of glycine and 5,10-methylene-THF

Direct effect of UA on neutrophils MSU crystals induce neutrophil migration (47), playing a critical role in acute inflammatory responses, including infections and sterile injuries characterized by crystal deposition