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doi: 10.1016/j.ijpharm.2013.03.054, 125

The structures of VNARs C4 and D1 each represent a facet of shark-derived therapeutics that apply to multiple disease contexts

Heart failure therapy by GLP-1RAs Although a meta-analysis of large-scale clinical trials suggested that GLP-1RAs reduce heart failure hospitalizations (HHF) by approximately 10% in patients with diabetes at high cardiovascular risk [22, 23], the treatment effects on the risk of HHF in individual trials other than AMPLITUDE-O were not significant (Tables 1, 2)