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In hypoxia, the increased expression of the mitochondrial gene might involve the phosphorylation of the AKT signaling pathway, rather than the activation of ERK that is activated in a traumatic neuronal injury through PKC (77)

Drug sensitivity analysis further demonstrated that patients in the high and low gene score groups exhibited significant differences in sensitivity to various anticancer agents ( Figure 10G )

In hemodialysis patients with severe secondary hyperparathyroidism, Urea et al., observed that hematocrit values correlated more strongly with serum IGF-1 levels than with serum EPO levels.125 Interestingly, residual hematopoietic function has been observed in some anephric patients, suggesting the involvement of stimulators beyond renal EPO

Loss of VGLUT1 and VGLUT2 in the prefrontal cortex is correlated with cognitive decline in Alzheimer disease