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4.2.2 Tolerance to Heat, Oxygen, and Light SAG exhibits enhanced thermal stability compared to GSH, tolerating standard manufacturing temperatures with minimal degradation

WT mitochondrial branches seem to be 25% longer than those observed in ctl-2(ua90)II strain at OGT

To determine the downstream signaling pathway in the host that responds to the glucose fed bacteria diet, we screened distinct pathways induced by oxidative stress (gst-4, sod-3) , or heat stress (hsp-16.2) , the mitochondrial UPR (hsp-6) 28,29 , the glyoxalase system (glod-4, gcs-1) , the transcription factor skn-1 30 , and the insulin/IGF-1 signaling pathway FOXO, daf-16 (Figure 3a and Supplementary Figure S3a)

It was found that dietary GSH can enhance antioxidant capacity and mRNA expression of tight junction protein with the consequence of improvement in growth performance of weaned piglets challenged by diquat, especially at the dose of 100 mg/kg of supplementation ( Degradation and oxidation of GSH in the gastrointestinal tract In the current study, CYS and CYSS were not detected in the stomach content of the CON group but can be detected in the LGSH and HGSH groups both on d5 and d14, which could indicate that CYS originates from GSH degradation in the stomach