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Methods Eligibility criteria The PICOS strategy was defined as follows: P (participants) human subjects, I (interventions) oral LC treatment, C (comparisons) between supplementation and placebo, supplementation and control, or pre- and post- supplementation, O (outcomes) muscle variables, and S (study design) randomized controlled trials, non-randomized controlled trials, non-randomized non-controlled trials

*Depending on growth conditions, a single Brazil nut could contain exceedingly high levels of selenium

The dose of L-carnitine administered intravenously was 1000 mg 3 weekly (Table 2)