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Nanoparticles mediating the sustained puerarin release facilitate improved brain delivery to treat Parkinsons disease

These molecules are at the heart of how our cells function, but as we age, our natural levels tend to decline

The present study investigated three less common 4-methoxy-substituted cathinones, namely 4MeO-NE-BP (4-methoxy- N -ethylbutyrophenone, 4-methoxy- N -ethylbuphedrone), 4MeO-P-BP (4-methoxy--pyrrolidinobutyrophenone, also known as 4-MeOPBP or 4-methoxy--PBP), and 4MeO-P-VP (4-methoxy--pyrrolidinovalerophenone, also known as 4-MeOPVP or 4-methoxy--PVP), and three novel 4-methylthio analogs 4MeS-NE-BP (4-methylthio- N -ethylbutyrophenone, 4-methylthio- N -ethylbuphedrone), 4MeS-P-BP (4-methylthio--pyrrolidinobutyrophenone), and 4MeS-Mor-PrP (4-methylthio-2-morpholinopropiophenone)

When cell turnover slows with age or when dead cells build up on the surface, the complexion can look dull, regardless of pigment levels