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K.MoselerA.SchwarzlnderM.et al (2019)

While it was long assumed that patients simply suffered from systemic glutathione depletion, a landmark 2025 study published in the Proceedings of the National Academy of Sciences (PNAS) uncovered a more complex reality

Milk thistle extract (Silymarin) Supports production of super antioxidant enzymes in the liver

Across multiple independent cohorts (Table 1), UC is consistently associated with increased relative abundance of Proteobacteriaparticularly the Enterobacteriaceae alongside reduced levels of health-associated groups such as Bifidobacterium , Lachnospiraceae, and Verrucomicrobia (e.g., Akkermansia