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Specifically, the epidermal thickness in the DBP-H group was similar to that in the DBP-Lip groups and the DBP-Lip-Gel-L group, and it was significantly thinner than that in the Model group

Meanwhile, knockdown of REST significantly increased GSH synthesis, restored GPX4 expression, and ultimately attenuated ferroptosis, which had an additive effect on the ferroptosis inhibitors Fer-1 and DFO