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Environmental irritants from city traffic, weather conditions, pesticides on our food, chemicals in our drinking water, alcohol use, and endocrine disruptors in food packaging and hygiene products all contribute to our total toxin load

If needed, supplements can be considered under medical guidance

doi: 10.1080/2162402X.2018.1466018 78 HoE.ClarkeJ

While antipsychotic drugs remain the mainstay of treatment, a substantial proportion of people do not have an adequate clinical response to such medications (Howes et al., 2012a, b), necessitating a better understanding of the underlying neurobiology and the development of new approaches to treatment